Aug. 19, 2014

Pioneering 3D printing biology company Organovo announced that it has passed a major drug test with the company's 3D bioprinting technology. In collaboration with a major pharmaceutical company, Organovo demonstrated that its 3D Human Liver System could detect the toxicity of a drug that had previously been deemed safe in standard preclinical animal studies and in vitro toxicity tests but caused liver damage upon clinical use. Traditionally the toxic profile of the compound was only discovered after use in a large number of patients and after significant expense.

Keith Murphy, chairman and chief executive officer of Organovo, commented on the results: "Organovo met a key challenge in this recent quarter. While we knew our liver tissue showed metabolic activity and basic toxicology results comparable to native tissue, we had to ask the question: could it be predictive of drug problems where other methods have failed? These results demonstrate clearly for the first time that our tissue has been able to detect drug-induced liver injury that other methods in the past failed to predict. With this data in hand, we are continuing to push progress in the commercialization of our 3D Liver Tissue. We remain on track for commercial release of our 3D Human Liver Tissue later this calendar year."

Organovo focused on using 3D bioprinting technology to design and create functional, 3D human tissues. On April 10th, the Company announced results of its initial study of 3D breast tissues generated with its NovoGen MMX Bioprinter in breast cancer models, which demonstrated that utilizing 3D tissues may enable researchers to make compartment-specific assessments (i.e., epithelium, stroma, and vasculature) of drug response - something that is not currently possible outside of in vivo models.

The company intends to launch its 3D Liver tissue and generate revenues before December 2014.

 

Posted in 3D Printing Technology

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