Jan.14, 2014

The cost of research and development in the drug industry — the cost of clinical trials in particular — is rising significantly. Still more than 95% of the experimental medicines that are studied in humans fail to be both effective and safe.

The good news is soon it will be possible to test drugs directly on 3D printed functional living tissues.

Bio 3D printing company Organovo announced today that they are joining together with two institutes from the National Institutes of Health (NIH) to help scientists develop more reliable tools for bringing safer, more effective treatments to patients on a faster timeline.

Organovo is collaborating with the National Center for Advancing Translational Sciences (NCATS) and the National Eye Institute (NEI) to develop better and more clinically predictive tissue models. Organovo will collaborate with NCATS and NEI in using the NovoGen Bioprinting platform to create three-dimensional, architecturally correct, functional living tissues.

"Researchers who develop new therapies for patients are too often hampered by animal models and traditional cell culture models that are poor predictors of drug efficacy and toxicity in human beings," says Keith Murphy, Organovo's Chief Executive Officer. "Our 3D printer creates living human tissues that more closely reproduce in vivo human tissues. In collaboration with NIH, which has worked to highlight and address the critical need for better models that can lead to better drugs, we hope to create tissue models that give researchers a much more accurate view of how drugs will behave in human beings before those drugs ever enter clinical trials."

Both NCATS and NEI will work with Organovo to develop a printable eye tissue. "This technology could provide us with a renewable and easy-to-manipulate source of functional eye tissue," said NEI Director Paul A. Sieving, M.D., Ph.D. "Printable eye tissue could be used to identify disease pathways and to screen for and discover new therapeutic drugs." Meanwhile NCATS also plans to develop additional tissue models that complement and leverage their current Tissue Chip and compound screening programs.

Posted in 3D Printing Company



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alvaro wrote at 1/15/2014 1:51:05 AM:

This partnership will improve tissue engineering , and maybe in a near future they will print fully functional organs .

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